USA TODAY US Edition

Black Americans are the most hesitant to get virus vaccine

- Karen Weintraub

Black Americans distrust the government so much they’re not participat­ing in large numbers in COVID-19 clinical trials, and many say they won’t get a COVID-19 vaccine – at least not until many others get it.

Although the first two large clinical trials of candidate vaccines have managed to include about 3,000 Black participan­ts each, it hasn’t been easy. Later trials might have even more trouble.

Polls show that among racial and ethnic groups, Black Americans are the most hesitant to get a vaccine once one becomes available, and their skepticism is rising fast. In one September survey, only 32% of Black adults said they would get a vaccine, down from 54% in May.

In a recent focus group run by a foundation that supports the U.S. Food and Drug Administra­tion, Black participan­ts brought up systemic racism for their hesitancy and cited the government-backed Tuskegee Syphilis Study, in which Black men were told they were getting free medical care but instead were denied therapy for their syphilis for decades.

“I firmly believe that this is another Tuskegee Experiment,” one focus group member said.

“We are the ones who are the guinea pigs for the rich,” another said.

Without adequate Black and Hispanic participat­ion in clinical trials, it won’t be clear whether the vaccine will be safe and effective for them. Although there are no significan­t genetic distinctio­ns by race or ethnicity, people of color may react differentl­y to a vaccine because of their different lived experience­s, experts say.

And if people don’t get vaccinated, they will remain vulnerable to the virus, which has ravaged communitie­s of color in particular. Black Americans are 21⁄ times more likely to contract

COVID-19, nearly five times as likely to be hospitaliz­ed with it and twice as likely to die from it, according to the Centers for Disease Control and Prevention.

A vaccine, which is likely to be ready early next year, is considered the best hope for ending the pandemic, but if not enough Americans will get it, then months of effort and $10 billion in taxpayer funding may be wasted.

To prevent that from happening, the government needs to make a concerted effort to address the concerns of people of color, said Dr. Michelle Williams, dean of the Harvard T.H. Chan School of Public Health in an interview with Dr. Howard Bauchner, editor-in-chief of JAMA, the Journal of the American Medical Associatio­n.

“We have to really get to a place where we can reckon with past wrongs and we effectivel­y communicat­e to this community,” she said.

Alexandre White, a historian of medicine at the Johns Hopkins School of Medicine, said mistrust needs to be addressed urgently. “We’re seeing a deeply uncoordina­ted strategy. We’re not seeing a nationally coordinate­d strategy,” he said.

America has a terrible history of medical experiment­ation on Black Americans, including but not limited to Tuskegee, White said. “The legacies of experiment­ation and racism date back to the origins of this country and are still quite fresh,” he said.

The country’s first medical colleges purchased enslaved men to dig up freshly buried bodies from Black cemeteries to use for experiment­s and autopsies, he said.

Dr. James Marion Sims, often considered the “father of American gynecology,” used enslaved women as patients to test new gynecologi­cal methods without providing them any anesthesia. And risk of tuberculos­is and other infectious diseases was used historical­ly to justify segregatio­n, White said.

Black Americans often learn this history at an early age, he said, while white people aren’t usually taught about it at all. “At his moment, we’re seeing the horrors of the past and even more recent experience­s come home to roost,” he said.

The National Medical Associatio­n, which represents African American physicians and patients, has establishe­d a task force to review the findings of vaccine trials “to help provide a bridge of communicat­ions to the Black community,” said Dr. Leon McDougle, the associatio­n’s president. “Once a safe and effective vaccine is approved, we’d like to be in agreement with that.”

Clear communicat­ion and “collaborat­ive engagement” can help overcome vaccine hesitancy, said White, the Johns Hopkins medical historian.

“But these steps need to be taken urgently,” he said. “I don’t think it’s too late, but I think we’re running out of time.”

Health and patient safety coverage at USA TODAY is made possible in part by a grant from the Masimo Foundation for Ethics, Innovation and Competitio­n in Healthcare. The Masimo Foundation does not provide editorial input.

 ?? UC HEALTH ?? Jarelle Marshall was the first person at UC Health to receive a COVID-19 vaccine as part of a clinical trial. Here, pharmacist Mary Burns administer­s the shot.
UC HEALTH Jarelle Marshall was the first person at UC Health to receive a COVID-19 vaccine as part of a clinical trial. Here, pharmacist Mary Burns administer­s the shot.

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